Hi Amit,
Thank you for posting your question in the Microsoft community.
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I understand that you are not able to install the drivers for Umax ASTRA 4600. Let me know if this incorrect.
The device you have mentioned is not compatible with Windows 8 refer to the link.
You may try to download the drivers designed for a previous version of Windows and then install using the compatibility mode in Windows 8.
a)Enter the Start screen
b)Press Windows key + C on your keyboard to show the Charms bar (If you have a touchscreen: Touch the right edge of your screen and slide your finger to the center of the screen to show the Charms bar)
c)Search for Troubleshooting, Click Settings in the right column.
Umax Astra 2500 Scanner Drivers
d)Click Troubleshooting. Click Run programs made for previous versions of Windows
e)Click Next, select Not Listed. Click Next
f)Click Browse and select the installer that you downloaded using the link above.
Umax Astra
g)Click Next, click Troubleshoot program
h)Check The program worked in earlier versions of Windows but won't install or run now box
i)Click Next, select the last known working operating system for this driver (probably Window 7)
j)Click Next
Umax Astra 2500 Scanner Driver Free Download
Let us know of this helped.